WHAT ARE THE EFFECTS OF THIS DRUG? ↓ Weight 9.9 to 14.08 pounds in 30 weeks with weekly injection doses of 0.5 mg or 1 mg respectively (1263) ↓ Weight 14.08 pounds in 26 weeks with once weekly injection of 1 mg (1231) ↓ Weight 11 pounds in 12 weeks with once weekly injection of 1 mg in obese people. (1232) A small study of 30 obese people found after a standardized breakfast, semaglutide, compared with placebo (no drug), led to a lower free will energy (calorie) intake during lunch (−1255 kJ; P