MAR-Topiramate CA

WHAT ARE THE EFFECTS OF THIS DRUG?
↓ -5 % body weight loss in 32 weeks with dose of 150mg per day (789)
↓ -9.1% body weight loss in 1yr, dose 256 mg/day, 61% of people lost at least 5 % weight (790)
↓ -7.0, -9.1, and -9.7% body weight with Doses of 96, 192, and 256 mg/day. One year study (790)
↓ -13.2 pounds in 16 weeks with dose of 175 mg per day representing -5.8 % body weight loss (791)
↓ Weight loss increases with longer duration of therapy, higher doses, and higher BMI (790 to 794)
↓ -5.0%, -4.8%, -6.3%, and -6.3% in 24 weeks with dose of 64, 96, 192, and 384 mg/day (792)
↓ Greater percentages of people lost at least 5% or 10% of body weight compared with placebo (792)
↓ -5.72 pounds in 12 week study vs placebo with dose of max tolerated up to 400 mg/day (795)
↓ -8.36 pounds (time period not specified) Meta-analysis (700)
Generic Name: Topiramate

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