WHAT ARE THE EFFECTS OF THIS DRUG?
↑ 1.1 pounds average in 6 months (109)
↑ 3.3 pounds average in 50 months (110, 111)
↑ 1.1- to 7.7 pounds in 6 to 12 months (36)
↑ 2.42 pounds average in 45 months with dose of 200 mg per day (189)
↑ 3.3 pounds average in 208 weeks study of 3,234 people (190)
↑ 1.1 pounds average in 26 weeks in women with doses of 50 to 200 mg per day (191)
↑ 1.54 pounds average in 26 weeks in men with doses of 50 to 200 mg per day (191)
↑ 0.88 to 7.7 pounds in 6 to 12 months in a systematic analysis of 8 studies (36)
Beta-blockers increased risk of developing diabetes by 48% [1.48X (1.48 times)]. Nazarzadeh M et al, 2021, Lancet, meta-analysis (2137) and comment by Volpe M et al, 2022 European Heart Journal (2125)
Several studies have found type 2 diabetes to be a risk equivalent for heart disease. We can safely claim that having diabetes is a significant risk factor for heart disease. (1606-1624)
Beta-blockers change carbohydrate metabolism, increase blood sugar levels, reduce tissue insulin sensitivity, and increase triglyceride (TG) concentrations while reducing HDL cholesterol (the good heart protective type of cholesterol). (592, 593, 2128)
Generic Name: Metoprolol