WHAT ARE THE EFFECTS OF THIS DRUG?
↓ or Generally weight neutral and sometimes mild weight loss for metformin when given alone (672)
↓ -2.42 pounds average vs placebo (no drug) time not specified in Meta-analysis study for metformin when given alone(700)
↓ Weight of −4.1% to −4.2% at 104 weeks with Canagliflozin given alone (575)
↓ Weight loss plateaus after 26 -34 weeks with Canagliflozin given alone (568)
* Warnings for Canagliflozin and (SGLT2) Inhibitors:
↑ Ketoacidosis risk (difficulty breathing, vomiting, abdominal pain, confusion, sleepiness)
↑ Risks of serious UTI (urinary tract infections) and
↑ Risk of bone fractures
↑ Risk of necrotizing fasciitis of the perineum (Fournier gangrene) is rare but potentially fatal.
Generic Name: Canagliflozin &
Metformin