WHAT ARE THE EFFECTS OF THIS DRUG?
↑ Median gain 2.64 pounds in 6 to 12 months with beta-blocker alone in a systematic analysis of 8 studies (36)
Beta-blockers increased risk of developing diabetes by 48% [1.48X (1.48 times)]. Nazarzadeh M et al, 2021, Lancet, meta-analysis (2137) and comment by Volpe M et al, 2022 European Heart Journal (2125
Several studies have found type 2 diabetes to be a risk equivalent for heart disease. We can safely claim that having diabetes is a significant risk factor for heart disease. (1606-1624)
Most Beta-blockers change carbohydrate metabolism, increase blood sugar levels, reduce tissue insulin sensitivity, and increase triglyceride (TG) concentrations while reducing HDL cholesterol (the good heart protective type of cholesterol). (592, 593, 2128)Nebivolol and carvediol are unique third generation beta blockers that have antioxidant effects and free radical scavenging ability that may translate into heart protective effects. (2152, 2153)
Valsartan is typically weight neutral

Generic Name: Nebivolol &
Valsartan